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  6. Thermo Scientific Chemicals Ampicillin, Ready-to-Use aqueous soln., 100mg/mL, 0.2 micron filtered

Thermo Scientific Chemicals Ampicillin, Ready-to-Use aqueous soln., 100mg/mL, 0.2 micron filtered

Catalog Number 15440677
1050.84 SEK valid until 2024-09-30
Use promo code "23252" to get your promotional price.

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Quantity:
10 mL
69-53-4
C16H19N3O4S
349.405
AVKUERGKIZMTKX-NJBDSQKTSA-N
6249
CHEBI:28971
(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C
69-53-4
C16H19N3O4S
349.405
AVKUERGKIZMTKX-NJBDSQKTSA-N
6249
CHEBI:28971
(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C

Description

Ampicillin, CAS # 69-53-4, is structurally related to penicillin and is considered to be a semi-synthetic antibiotic with antibacterial activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Ampicillin is a broad-spectrum, semi-synthetic, β-lactam penicillin with bactericidal activity. It acts against several gram-positive and -negative infections
  • This compound binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. This inactivation interferes with the cross-linkage of peptidoglycan chains essential for bacterial cell wall strength and rigidity. Consequently, there is an interruption in the bacterial cell wall synthesis which results in the weakening of the bacterial cell wall causing cell lysis

Application

  • In laboratory experiments, it is commonly used as a selector reagent for transformed cells expressing β-lactamase. The ampicillin-resistant gene (ampR) catalyzes the hydrolysis of the β-lactam ring of ampicillin and naturally detoxifies the drug
  • Ampicillin is commonly used as a selection marker for E. coli and other bacteria during plasmid DNA isolation, protein expression, and gene cloning
TRUSTED_SUSTAINABILITY
Type Ampicillin
Physical Form Liquid
Odor Odorless
Color Yellow
Quantity 10 mL
Sensitivity Light sensitive
Chemical Name or Material Ampicillin, eady-to-Use aqueous soln., 100mg/mL, 0.2 micron filtered

RUO – Research Use Only

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