missing translation for 'onlineSavingsMsg'
Learn More
Learn More
H3K4me3 Monoclonal Antibody (G.532.8), Invitrogen™
Rabbit Monoclonal Antibody
Brand: Invitrogen MA511199
This item is not returnable.
View return policy
Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with methylated histone H3 Lys9, Lys27, Lys36 or methylated histone H4 Lys20.
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Specifications
| H3K4me3 | |
| Monoclonal | |
| 121 μg/mL | |
| 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5 | |
| P61830, P68431, P68433, P84228, Q71DI3 | |
| H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7, HHT1, His3:CG31613 | |
| Synthetic peptide corresponding to the amino terminus of histone H3 in which Lys4 is tri-methylated | |
| 100 μL | |
| Primary | |
| Drosophila, Human, Mouse, Non-human Primate, Rat, Yeast | |
| Antibody | |
| IgG |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Peptide Array, Western Blot | |
| G.532.8 | |
| Unconjugated | |
| H3C1 | |
| B0035.7; BUR5; CELE_T10C6.12; CG31613; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; F07B7.10; F07B7.3; F08G2.2; F17E9.13; F35H10.1; F45F2.4; F54E12.5; F55G1.10; H02I12.7; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3 K4; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3b; h3-5; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 126961, 260423, 318847, 319150, 319152, 333932, 360198, 8350, 8356, 8357, 8358, 852295, 8968, 97114 | |
| -20°C | |
| Liquid |