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Capsazepine, Tocris Bioscience™

Product Code. 18025122
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Vanilloid receptor antagonist; also activator of ENaCδ

Selective vanilloid receptor antagonist (Ki = 3.2 μM). Inhibits carrageenan inflammation-induced hyperalgesic responses in the rat. Also activates amiloride-sensitive epithelial Na+ channel ENaCδ.

Chemical Identifiers

CAS 138977-28-3
Molecular Formula C19H21ClN2O2S
Molecular Weight (g/mol) 376.899
InChI Key DRCMAZOSEIMCHM-UHFFFAOYSA-N
Synonym capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464
PubChem CID 2733484
ChEBI CHEBI:70773
IUPAC Name N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
SMILES C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O

Specifications

Quantity 10 mg
Formula Weight 376.9
Percent Purity >99%
Chemical Name or Material Capsazepine
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