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Invitrogen™ Human FBXL20 Synthetic Peptide

Produktkod. 15378760
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Kvantitet:
50 μg
Förpackningsstorlek:
50µg
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Product Code. 15378760

Brand: Invitrogen™ PEP0606

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Description

Synthetic Peptide

SCRAPPER Synthetic Peptide, PEP-0606, from Invitrogen.

Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane. Scrapper has orthologs in C. elegans, D. melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species. Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission. This identifies protein degradation as a mechanism for holding synaptic communication in check.
TRUSTED_SUSTAINABILITY

Specifications

Gen-ID (Entrez) 84961
Art Human
Reningsmetod purified
Tillträdesnummer Q96IG2
Vanligt namn Human FBXL20
Koncentration 200 μg/mL
Innehåll och lagring -20°C
Beskrivning Synthetic Peptide
Formatera Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
För användning med (applikation) Blocking Assay, Control
Gensymbol FBXL20
Frystorkat material No
Konserveringsmedel 0.02% sodium azide
Produkttyp Peptide
Kvantitet 50 μg
Regulatorisk status RUO - research use only
Förvaringsbuffert PBS
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