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Invitrogen™ MAP2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA517646
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Beskrivning
It is not recommended to aliquot this antibody. PA5-17646 was successfully used to detect MAP2 in neurons differentiated from H9 ESC derived NSCs. This antibody is not cross-reactive with tau.
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).
Specifikationer
| MAP2 | |
| Polyclonal | |
| Unconjugated | |
| Map2 | |
| a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 17756, 25595, 4133 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 73.6 μg/mL | |
| 0.01M HEPES with 100μg/mL BSA, 0.15M NaCl, 50% glycerol and no preservative; pH 7.5 | |
| P11137, P15146, P20357 | |
| Map2 | |
| Synthetic peptide corresponding to carboxy-terminal residues of human MAP2. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Monkey, Rat | |
| Antibody | |
| IgG |
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