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Invitrogen™ NY-ESO-1 Monoclonal Antibody (E978)
Mouse Monoclonal Antibody
Brand: Invitrogen™ 356200
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Beskrivning
This antibody can react specifically with the 23 kDa NY-ESO-1 protein. During development reactivity was confirmed with human SKMEL-37 melanoma cells.
NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor specific shared antigen with distinctive immunogenicity. The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen. The NY-ESO-1 has been detected in normal testis and in a range of human tumor types. NY-ESO-1 reactivity in testis is restricted germ cells, particularly in the spermatogonia.
Specifikationer
| NY-ESO-1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| P78358 | |
| CTAG1A | |
| Human NY-ESO-1 recombinant protein. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| E978 | |
| Unconjugated | |
| CTAG1A | |
| Autoimmunogenic cancer/testis antigen NY-ESO-1; cancer/testis antigen 1; cancer/testis antigen 1A; cancer/testis antigen 1-A; cancer/testis antigen 6.1; CT6.1; CTAG; CTAG1; CTAG1A; CTAG1B; ESO1; l antigen family member 2; LAGE2; LAGE-2; LAGE2A; LAGE2B; New York Esophageal Squamous Cell Carcinoma 1; NY-ESO-1 | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 246100 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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