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Tocris Bioscience™ UNC 1999
Potent and selective EZH2/EZH1 inhibitor
Brand: Tocris Bioscience™ 4904/50
8834.33 SEK valid until 2024-12-16
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This item is not returnable.
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Description
UNC 1999 is a potent and SAM-competitive EZH2/EZH1 lysine methyltransferase inhibitor (IC50 values are 10 and 45 nM, respectively). Selective for EZH2/EZH1 over a panel of other methyltransferases and non-epigenetic targets. Reduces H3K27me3 levels in vitro. Prolongs survival of MLL-AF9 bearing mice. Orally bioavailable.Negative Control also available.
Specifications
| >99% | |
| UNC 1999 | |
| UNC 1999 |
| 50 mg | |
| 569.74 |
For Research Use Only