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  7. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%, Thermo Scientific Chemicals

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%, Thermo Scientific Chemicals

Product Code. 11419742
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Quantity:
1 g
5 g
25 g

Description

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.

Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 25952-53-8
Molecular Formula C8H18ClN3
Molecular Weight (g/mol) 191.70
MDL Number MFCD00012503
InChI Key FPQQSJJWHUJYPU-UHFFFAOYSA-N
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride, edc.hcl, edci, edc hydrochloride, wsc hcl, edac hydrochloride, edac, hydrochloride, 1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride, edcl, edac hcl
PubChem CID 2723939
IUPAC Name 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;hydrochloride
SMILES Cl.CCN=C=NCCCN(C)C

Specifications

Melting Point ∽113°C
Linear Formula CH3CH2N=C=N(CH2)3N(CH3)2·HCl
Quantity 5 g
Beilstein 5764110
Sensitivity Moisture sensitive
Solubility Information Soluble in acetonitrile dichloromethane,dimethylformamide,and tetrahydrofuran. Slightly soluble in water.
Formula Weight 191.7
Percent Purity ≥98%
Chemical Name or Material 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride

Safety and Handling

compliance-icons compliance-icons compliance-icons
Product Identifier
  • 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 3
  • Acute toxicity Category 4
  • LONG-TERM AQUATIC HAZARD Chronic 1
  • ACUTE AQUATIC Acute 1
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity after repeated exposure Category 2
 Hazard Statement
  • H302-Harmful if swallowed.
  • H311-Toxic in contact with skin.
  • H315-Causes skin irritation.
  • H317-May cause an allergic skin reaction.
  • H319-Causes serious eye irritation.
  • H373-May cause damage to organs.
  • H400-Very toxic to aquatic life.
  • H410-Very toxic to aquatic life with long lasting effects.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
 Supplemental information
  • MIXTURE LIST-Contains : N'-(ethylcarbonimidoyl)-N,N-dimethyl-1,3-Propanediamine monohydrochloride

RUO – Research Use Only

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