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1-Boc-piperazine, 99%, Thermo Scientific Chemicals

689.00 SEK - 5370.00 SEK

Chemical Identifiers

CAS 57260-71-6
Molecular Formula C9H19N2O2
Molecular Weight (g/mol) 187.26
MDL Number MFCD00075265
InChI Key CWXPZXBSDSIRCS-UHFFFAOYSA-O
Synonym 1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl ester
PubChem CID 143452
IUPAC Name tert-butyl piperazine-1-carboxylate
SMILES CC(C)(C)OC(=O)N1CC[NH2+]CC1
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Product Code Brand Quantity Price Quantity & Availability  
11378076
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Thermo Scientific Alfa Aesar
L13363.03
1 g
689.00 SEK
1g
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11388076
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Thermo Scientific Alfa Aesar
L13363.06
5 g
1620.00 SEK
5g
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11398076
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Thermo Scientific Alfa Aesar
L13363.14
25 g
5370.00 SEK
25g
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Description

Description

1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

Solubility
Soluble in ethyl acetate, methanol and water.

Notes
Hygroscopic. Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
Specifications

Chemical Identifiers

57260-71-6
187.26
CWXPZXBSDSIRCS-UHFFFAOYSA-O
143452
CC(C)(C)OC(=O)N1CC[NH2+]CC1
C9H19N2O2
MFCD00075265
1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl ester
tert-butyl piperazine-1-carboxylate

Specifications

57260-71-6
C9H19N2O2
879985
1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl ester
CWXPZXBSDSIRCS-UHFFFAOYSA-O
tert-butyl piperazine-1-carboxylate
143452
99%
44°C to 48°C
MFCD00075265
Air Sensitive
Soluble in ethyl acetate,methanol and water.
CC(C)(C)OC(=O)N1CC[NH2+]CC1
187.26
186.26
1-Boc-piperazine
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Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

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Recommended Storage : Ambient temperatures; Store under Nitrogen

SDS
Documents

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Product Certifications

RUO – Research Use Only