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2-Bromoisobutyryl bromide, 97%, Thermo Scientific Chemicals
Description
2-Bromoisobutyryl bromide is used to prepare N-protected halodienamide, which provides four- and five-membered lactams in the presence of copper(I) and a tertiary amine. Further, it is used as atom transfer radical polymerization(ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide. It is also used in preparation of polycaprolactone macroinitiators through reaction with oligomeric caprolactone diol and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
2-Bromoisobutyryl bromide is used to prepare N-protected halodienamide, which provides four- and five-membered lactams in the presence of copper(I) and a tertiary amine. Further, it is used as atom transfer radical polymerization(ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide. It is also used in preparation of polycaprolactone macroinitiators through reaction with oligomeric caprolactone diol and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface.
Solubility
Miscible with acetone and carbon disulfide.
Notes
Moisture sensitive. Incompatible with strong oxidizing agents and strong alkalis.
Specifications
Specifications
| Density | 1.86 |
| Boiling Point | 160°C to 162°C |
| Flash Point | >110°C (230°F) |
| Odor | Acrid |
| Refractive Index | 1.5095 |
| Quantity | 25 g |
| UN Number | UN3265 |
| Beilstein | 1746128 |
| Sensitivity | Moisture sensitive |
| Solubility Information | Miscible with acetone and carbon disulfide. |
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Safety and Handling
- 2-Bromoisobutyryl bromide
- Danger
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 1
- Germ cell mutagenicity Category 1B
- Skin corrosion/irritation Category 1 B
- Skin sensitiser Category 1
- H302-Harmful if swallowed.
- H314-Causes severe skin burns and eye damage.
- H317-May cause an allergic skin reaction.
- H318-Causes serious eye damage.
- H340-May cause genetic defects.
- P201-Obtain special instructions before use.
- P202-Do not handle until all safety precautions have been read and understood.
- P260-Do not breathe dust/fume/gas/mist/vapours/spray.
- P264-Wash face, hands and anyexposed skin thoroughly after handling.
- P270-Do not eat, drink or smoke when using this product.
- P271-Use only outdoors or in a well-ventilated area.
- P272-Contaminated work clothing should not be allowed out of the workplace.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- P330-Rinse mouth.
- P331-Do NOT induce vomiting.
- P363-Wash contaminated clothing before reuse.
- P403+P233-Store in a well-ventilated place. Keep container tightly closed.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
- MIXTURE LIST-Contains : 2-bromo-2-methyl-propanoyl bromide
RUO – Research Use Only