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Thermo Scientific™ TheraPure™ 2'-MOE-T Phosphoramidite, 28-400 finish bottle

2'-MOE-T CEP is a phosphoramidite containing 5' DMT and the nucleoside thymidine (T, or 5-me-U) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis.

Specifications

For Use With (Equipment) MerMade Synthesizers
Product Type 2in-MOE-T CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Thymidine (T)
Reagent Features 2in-MOE modified
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
17937122
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Thermo Scientific™
27-1021-11
1 g N/A
N/A
17907132
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Thermo Scientific™
27-1021-82
2 g N/A
N/A
Description

Description

2'-MOE-T CEP is a phosphoramidite containing 5' DMT and the nucleoside thymidine (T, or 5-me-U) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methoxy-ethyl (MOE) modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-thymidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Molecular formula: C43H55N5O10P
Base: T
Formula weight: 819.0 g/mol
CAS number: 163878-63-5
HPLC purity: ≥99%; M-11 Impurity ≤0.01%
31P NMR purity: ≥99%

Specifications

Specifications

MerMade Synthesizers
Store in freezer (at or below -20°C).
2in-MOE modified
99%
TheraPure™
TheraPure™
2in-MOE-T CEP
Thymidine (T)
Room Temperature
Phosphoramidite
RNA
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