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DiscoverX PathHunter™ U2OS MERTK Functional Assay
The PathHunter™ U2OS MERTK Functional Assay measures MERTK receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1151C3
This item is not returnable.
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Description
The PathHunter™ MERTK FGFR2 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated MERTK dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses PK-tagged MERTK and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Receptor Clustering | |
| Cell Lines | |
| 2 Vials |
| U2OS | |
| Gas6 | |
| NM_006343.3 |
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DiscoverX PathHunter™ U2OS MERTK Functional Assay
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