Learn More
4-Methylumbelliferyl sulfate potassium salt, 98%, Thermo Scientific Chemicals
Description
4-Methylumbelliferyl sulfate potassium salt is a fluorometric substrate for the determination of sulfatase. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
4-Methylumbelliferyl sulfate potassium salt is a fluorometric substrate for the determination of sulfatase. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors.
Solubility
Soluble in water at 5mg/ml
Notes
Excitation wavelength, 334 nm; emission wavelength, 370nm (pH 10.4). Reaction product: excitiation wavelength, 360nm; emission wavelength, 449nm
Specifications
Specifications
| Color | White to Yellow |
| Quantity | 500 mg |
| Beilstein | 3803203 |
| Solubility Information | Soluble in water at 5mg/ml |
| Formula Weight | 294.32 |
| Percent Purity | 98% |
| Physical Form | Powder |
| Chemical Name or Material | 4-Methylumbelliferyl sulfate potassium salt |
Certificates
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
| Lot Number | Certificate Type | Date | Catalog Number |
|---|---|---|---|
| T25J045 | Certificate of Analysis | 24/10/2023 | J66160.ME,J66160.03,J66160.06 |
| S02J004 | Certificate of Analysis | 24/10/2023 | J66160.ME,J66160.03,J66160.06 |
| S20I002 | Certificate of Analysis | 29/07/2022 | J66160.ME,J66160.03,J66160.06 |
| Y15H040 | Certificate of Analysis | 12/04/2022 | J66160.ME,J66160.03,J66160.06 |
| Q15G008 | Certificate of Analysis | 08/12/2021 | J66160.ME,J66160.03,J66160.06 |
RUO – Research Use Only
Your input is important to us. Please complete this form to provide feedback related to the content on this product.