missing translation for 'onlineSavingsMsg'
Learn More
Thermo Scientific Chemicals 5-Azacytidine, 99% Product Code.: 10003160
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Carbohydrates
  5. Glycosyl compounds
  6. Thermo Scientific Chemicals 5-Azacytidine, 99%
SDS compliance-icons compliance-icons

Thermo Scientific Chemicals 5-Azacytidine, 99%

Product Code. 10003160
50 mg
Click to view available options
Quantity:
50 mg
1 g
This item is not returnable. View return policy

Product Code. 10003160

Brand: Thermo Scientific Chemicals 226620500

Request Bulk or Custom Format

Please to purchase this item. Need a web account? Register with us today!

565.16 SEK valid until 2025-12-31
Use promo code "25339" to get your promotional price.

 Explore more special offers
This item is not returnable. View return policy

Description

5-Azacytidine, CAS # 320-67-2, is an chemical analog of cytidine that acts as an inhibitor of DNA methyltransferase activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • 5-Azacytidine is a chemical analog of the nucleoside cytidine that incorporates into DNA and inhibits DNA methylation
  • At low doses, 5-azacytidine irreversibly binds the enzyme DNA methyltransferase (DNMT)

Applications

  • 5-Azacytidine has been used for cardiomyocyte differentiation from mesenchymal stem cells
  • It has been used as a potent DNMT inhibitor in the study of tumor cell proliferation and induction of gene expression following demethylation
  • 5-Azacytidine can globally change histone modification patterns
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 320-67-2
Molecular Formula C8H12N4O5
Molecular Weight (g/mol) 244.21
MDL Number MFCD00006539
InChI Key NMUSYJAQQFHJEW-KVTDHHQDSA-N
Synonym 5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
PubChem CID 9444
ChEBI CHEBI:2038
IUPAC Name 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
SMILES NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Specifications

CAS Min % 98.5
CAS Max % 100.0
Melting Point 228.0°C to 230.0°C
Color White
Infrared Spectrum Authentic
Assay Percent Range 98.5% min. (HPLC)
Packaging Glass bottle
Quantity 50 mg
Merck Index 15, 884
Specific Rotation + 40.00
Solubility Information Solubility in water: .. Other solubilities: soluble in methanol
Formula Weight 244.21
Percent Purity 99%
Physical Form Crystalline Powder
Chemical Name or Material 5-Azacytidine, 99%
Show More Show Less

Certificates

Certificates

A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.

5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberA0442045 Certificate TypeCertificate of Analysis Date31/01/2025 Catalog Number226620500,226620010
Lot NumberA0467600 Certificate TypeCertificate of Analysis Date31/01/2025 Catalog Number226620500,226620010
Lot NumberA0465977 Certificate TypeCertificate of Analysis Date09/09/2024 Catalog Number226620500,226620010
Lot NumberA0402846 Certificate TypeCertificate of Analysis Date16/12/2022 Catalog Number226620500,226620010
Lot NumberA0392462 Certificate TypeCertificate of Analysis Date15/12/2022 Catalog Number226620500,226620010

Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • 5-Azacytidine
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 4
  • Germ cell mutagenicity Category 1B
 Hazard Statement
  • H340-May cause genetic defects.
  • H302-Harmful if swallowed.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
SDS

RUO – Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Thermo Scientific Chemicals 5-Azacytidine, 99% >

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.