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  6. 5-Bromo-2'-deoxyuridine, 99%, Thermo Scientific Chemicals

5-Bromo-2'-deoxyuridine, 99%, Thermo Scientific Chemicals

Product Code. 15443647
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Quantity:
250 mg
1 g
5 g
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 59-14-3
Molecular Formula C9H11BrN2O5
Molecular Weight (g/mol) 307.10
MDL Number MFCD00006529
InChI Key WOVKYSAHUYNSMH-RRKCRQDMSA-N
Synonym 5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine
PubChem CID 6035
ChEBI CHEBI:472552
IUPAC Name 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O

Specifications

Melting Point ∽190°C (decomposition)
Quantity 250 mg
Beilstein 30395
Merck Index 14,1452
Solubility Information Soluble in water.
Optical Rotation +31° (c=1 in 0.1N HCl)
Formula Weight 307.1
Percent Purity 99%
Chemical Name or Material 5-Bromo-2'-deoxyuridine

RUO – Research Use Only

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