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Acetyl-CoA Carboxylase Monoclonal Antibody (143), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen 437100
This item is not returnable.
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Description
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Specifications
| Acetyl-CoA Carboxylase | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| Q13085 | |
| Acaca | |
| Recombinant protein derived from the C-terminus of human Acetyl CoA Carboxylase 1 (ACC-1) protein (accession # Q13085, NP_942131), which is identical to chimpanzee. This protein is also 99% similar to Rhesus monkey, 96% similar to pig and bovine and 95% similar to mouse and rat. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot | |
| 143 | |
| Unconjugated | |
| Acaca | |
| A1Z784_DROME; A530025K05Rik; Acac; Acaca; ACACAD; Acc; ACC1; ACCA; ACC-alpha; ACC-PA; ACC-PB; ACC-PC; ACC-PE; ACC-PF; ACC-PG; aceto-acetyl-CoA-thiolase; acetyl CoA carboxylase; acetyl coenzyme A carboxylase; Acetyl-CoA carboxylase; Acetyl-CoA carboxylase 1; acetyl-CoA carboxylase 265; acetyl-CoA carboxylase alpha; acetyl-CoA-carboxylase; acetyl-coenzyme A carboxylase; acetyl-coenzyme A carboxylase alpha; ACoT; Biotin carboxylase; CG11198; CG11198-PA; CG11198-PB; CG11198-PC; CG11198-PE; CG11198-PF; CG11198-PG; CG8723; dACC; DmACC; Dmel\CG11198; Dmel_CG11198; EC 6.3.4.14; EC 6.4.1.2; FBgn0043811; GH12002p; Gm738; I79_006999; unnamed protein product | |
| Mouse | |
| Protein A | |
| RUO | |
| 31 | |
| -20°C | |
| Liquid |
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