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Actin Muscle Monoclonal Antibody (HHF35), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA514084

Product Code. 11324983

  • 4000.00 SEK / 500µL

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Description

Description

This antibody reacts with actin from tissue extracts of uterus, ileum, aorta, diaphragm, heart and smooth muscle cells. It recognizes alpha-actin from skeletal, cardiac, and smooth muscle, and reacts with gamma actin from smooth muscle. This antibody will react with tumors from smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle tumors (rhabdomyomas and rhabdomyosarcomas). Staining of formalin-fixed tissues requires boiling in 1mM EDTA, pH 8.0, followed by cooling at room temperature for 20 min.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Actin Muscle
Monoclonal
Conc. Not Determined
tissue culture supernatant with 0.09% sodium azide
P62736, P62737, P62738, P63259, P63260, P63261, P63267, P63268, P63269, P68032, P68033, P68035, P68133, P68134, P68136
ACTA1, ACTA2, ACTC1, ACTG1, ACTG2
SDS extract of human myocardium
RUO
11459, 11464, 11465, 11468, 11475, 25365, 287876, 29275, 29437, 58, 59, 70, 71, 72, 81633
4° C
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
HHF35
Unconjugated
ACTA1
0610041G09Rik; AA959943; a-actin; AAT6; ACT; Act4; ACT-4; ACTA; ACTA1; ACTA1 protein; Acta2; Acta-2; ACTA3; ACTB; Actc; ACTC1; Actc-1; ACTE; Actg; Actg1; Actg2; ACTGE; actin; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 2, smooth muscle; actin alpha cardiac; actin alpha cardiac 1; actin alpha cardiac muscle 1; actin gamma 1; actin gamma 2, smooth muscle; actin homolog; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; actin, beta; actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; Actin, cytoplasmic type 5; actin, cytoplasmic, type 5; actin, gamma 1; actin, gamma 1 propeptide; ac
Mouse
500 μL
Primary
Human, Mouse, Rat
Antibody
IgG1 κ
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