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STEMCELL Technologies All-Trans Retinoic Acid

Retinoid pathway activator; Activates retinoic acid receptor (RAR)

Brand: STEMCELL Technologies 72262

Product Code. 15855521

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Description

All-Trans Retinoic Acid is a derivative of Vitamin A that functions as a ligand for the retinoic acid receptor (RAR, IC₅₀ = 14 nM)
RARs heterodimerize with retinoid X receptors (RXRs) and bind to retinoic acid response elements (RAREs) in DNA and act as transcription factors, altering gene expression
(Apfel et al.), Chambon)

Specifications

Synonym	ATRA; NSC 122758; Retinoic acid; Trans retinoic acid; Tretinoin; Vitamin A acid
Molecular Formula	C₂₀H₂₈O₂

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