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DR4 Monoclonal Antibody (DR-4-02), FITC, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA119757

Product Code. 11529262

  • 4180.00 SEK / 100µg

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Description

Description

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
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DR4 Monoclonal Antibody (DR-4-02), FITC, Invitrogen™ > 100 μg; FITC

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