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CD62L Mouse anti-Human, PE-CF594, Clone: Dreg 56, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 562301
This item is not returnable.
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Description
TheDREG-56 monoclonal antibody specifically binds to CD62L. CD62L is a 76-95 kDa glycoprotein that is also referred to as L-selectin or LECAM-1. CD62L is expressed on neutrophils, monocytes, T- and B-lymphocyte subsets and NK cells. The DREG-56 antibody recognizes the same antigen as LAM-1, and specifically inhibits >90% of binding of human lymphocytes to high endothelial venules (HEV) in frozen sections of peripheral, but not mucosal lymphoid tissue. It thus defines L-selectin as a human lymphocyte homing receptor for peripheral lymph node HEV.
This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red (eg 610/20-nm filter).
Specifications
| CD62L | |
| Monoclonal | |
| PE-CF594 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Supernatant from PMA-activated Human Peripheral Blood Leukocytes | |
| 100 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| Dreg 56 | |
| SELL; L-selectin; LSEL; LAM-1; LECAM-1; LEU8; LNHR; MEL-14; PLNHR; TQ-1 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
For Research Use Only.