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mGluR7 Polyclonal Antibody, Invitrogen™
Goat Polyclonal Antibody
Brand: Invitrogen PA519096
This item is not returnable.
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Description
This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| mGluR7 | |
| Polyclonal | |
| Unconjugated | |
| GRM7 | |
| 6330570A01Rik; BB176677; C030018L03; E130018M02Rik; FLJ40498; G protein-coupled receptor GRM7; G protein-coupled receptor, family C, group 1, member G; GLUR7; glutamate metabotropic receptor 7; glutamate receptor; glutamate receptor, metabotropic 7; Gpr1g; Gprc1g; GRM7; Metabotropic glutamate receptor 7; metabotropic glutamate receptor mGluR7; metabotropic glutamate receptor subtype 7b; MGLU7; mGlu7a receptor; MGLUR7; PPP1R87; protein phosphatase 1, regulatory subunit 87 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 2917 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q14831 | |
| GRM7 | |
| Synthetic peptide sequence (NCKLTISGSKKEDT ) corresponding to the internal amino acids of GRM7 | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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