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OLFM1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA528842
3003.48 SEK valid until 2025-03-29
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Description
Recommended positive controls: HepG2, mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Chicken (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
Specifications
| OLFM1 | |
| Polyclonal | |
| Unconjugated | |
| OLFM1 | |
| 1B426B; AMY; AW742568; D2Sut1e; neuroblastoma protein; neuronal olfactomedin-related ER localized protein; Noe1; Noel; Noel1; Noelin; Noelin 1; Noelin 2; NOELIN1; OlfA; olfactomedin 1; olfactomedin related ER localized protein; olfactomedin-1; OLFM1; Pancortin; pancortin 1; Pancortin 1-4; Pancortin3 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10439, 56177 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| O88998, Q99784 | |
| OLFM1 | |
| Synthetic peptide corresponding to a region within amino acids 421 and 485 of Human Noelin | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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Product Title
OLFM1 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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