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p300 Monoclonal Antibody (RW128), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA116608
This item is not returnable.
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Description
Suggested positive control: HeLa nuclear extract.
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Specifications
| p300 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| B2RWS6, Q09472 | |
| EP300 | |
| Fusion protein containing residues 1572-2371 of human p300. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Mustelid, Non-human Primate, Rat | |
| Antibody | |
| IgG1 κ |
| Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot | |
| RW128 | |
| Unconjugated | |
| EP300 | |
| A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2 | |
| Mouse | |
| Protein A | |
| RUO | |
| 170915, 2033, 328572 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |