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TNF RII/TNFRSF1B Mouse anti-Human, Clone: 22221, R&D Systems™

Mouse Monoclonal Antibody has been used in 8 publications

Brand: R&D Systems MAB226-500

Product Code. 15765084

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Description

TNF RII/TNFRSF1B Monoclonal specifically detects TNF RII/TNFRSF1B in Human samples. It is validated for Flow Cytometry, Neutralization, Immunocytochemistry.

Specifications

Antigen	TNF RII/TNFRSF1B
Classification	Monoclonal
Conjugate	Unconjugated
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Alias	CD120b, CD120b antigen, Etanercept, p75 TNF receptor, p75TBPII, p75TNFR, soluble TNFR1B variant 1, TNFBRp80 TNF-alpha receptor, TNF-R2, TNFR2TNFR1B, TNF-R75, TNFR80, TNFRII, TNF-RII, TNF-R-II, TNFR-II, TNFRSF1B, tumor necrosis factor beta receptor, tumor necrosis factor binding protein 2, Tumor necrosis factor receptor 2, tumor necrosis factor receptor superfamily member 1B, tumor necrosis factor receptor superfamily, member 1B, Tumor necrosis factor receptor type II
Host Species	Mouse
Purification Method	Protein A or G purified from ascites
Regulatory Status	RUO
Gene ID (Entrez)	7133
Reconstitution	Reconstitute at 0.5 mg/mL in sterile PBS.
Content And Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype	IgG2a

Applications	Flow Cytometry, Neutralization, Immunocytochemistry
Clone	22221
Dilution	Flow Cytometry 0.25 ug/10^6 cells, Neutralization 0.5-1.5 ug/mL, Immunocytochemistry 8-25 ug/mL
Gene Accession No.	P20333
Gene Symbols	TNFRSF1B
Immunogen	E. coli-derived recombinant human TNF RII Leu23-Asp257 Accession # P20333
Quantity	500 μg
Primary or Secondary	Primary
Test Specificity	Detects human TNF RII/TNFRSF1B in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) 4-1BB, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhFas, rhGITR, rhHVEM, rhLTR beta , rhNGF R, rhOPG, rhRANK, rhTNF RI, or recombinant mouse TNF RII is observed. Neutralizes the biological effect of rhTNF RII but not rhTNF RI.
Target Species	Human
Form	Ascites

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TNF RII/TNFRSF1B Mouse anti-Human, Clone: 22221, R&D Systems™

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