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BAD Monoclonal Antibody (E.564.7), Invitrogen™
Rabbit Monoclonal Antibody
Brand: Invitrogen MA514800
This item is not returnable.
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Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with related proteins.
The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Specifications
| BAD | |
| Monoclonal | |
| 27.9 μg/mL | |
| 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5 | |
| O35147, Q61337, Q92934 | |
| BAD | |
| Synthetic peptide corresponding to residues surrounding Pro102 of human Bad | |
| 100 μL | |
| Primary | |
| Human, Mouse, Non-human Primate, Rat | |
| Antibody | |
| IgG |
| Immunocytochemistry, Western Blot | |
| E.564.7 | |
| Unconjugated | |
| BAD | |
| AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 12015, 572, 64639 | |
| -20°C | |
| Liquid |
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Product Title
BAD Monoclonal Antibody (E.564.7), Invitrogen™ > 100 μL; Unconjugated
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