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Bay 11-7821, Tocris Bioscience™

Catalog Number 30001283
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Quantity:
10 mg
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Description

E2 ubiquitin (Ub) conjugating enzymes inhibitor

E2 ubiquitin (Ub) conjugating enzyme inhibitor. Inhibits the conjugation of Ub to a range of E2 enzymes. Inhibits E2 enzyme mediated IκBα phosphorylation and indirectly decreases NF-κb activity. Also reversibly activates MAPK signaling. Induces apoptosis of leukemic T cell and B-cell lymphoma cell lines. Also inhibits activation of NLRP3 inflammasome.
CAS 19542-67-7
Molecular Formula C10H9NO2S
MDL Number MFCD00712162
Quantity 10 mg
Synonym e-3-tosylacrylonitrile, e-3-p-toluenesulfonyl acrylonitrile, unii-4y5g2a4f6o, e-3-4-methylphenyl sulfonylprop-2-enenitrile, 3-p-toluenesulfonyl acrylonitrile, e, 3-4-methylphenylsulfonyl-2-propenenitrile, e-3-4-methylphenylsulfonyl-2-propenenitrile, e 3-4-methylphenyl sulfonyl-2-propenenitrile, 2e-3-4-methylphenyl sulfonyl prop-2-enenitrile, 2-propenenitrile, 3-4-methylphenyl sulfonyl-, 2e
InChI Key DOEWDSDBFRHVAP-KRXBUXKQSA-N
SMILES CC1=CC=C(C=C1)S(=O)(=O)\C=C\C#N
IUPAC Name (2E)-3-(4-methylbenzenesulfonyl)prop-2-enenitrile
Molecular Weight (g/mol) 207.25
PubChem CID 5353431
ChEBI CHEBI:85928
Formula Weight 207.25
Percent Purity >99%
Chemical Name or Material Bay 11-7821
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