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BEND3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA553659
This item is not returnable.
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Description
Immunogen sequence: CLPQLNDFFS RFWAQREMED SQPSGQVASF FEAEQVDPGH FLDNKDQEEA LSLDRSSTIA SDHVVDTQDL TEFLDEASSP GEFAVFLLHR LFPELFDHRK LGEQYSCYGD GGKQELDPQR LQIIRNYTEI YFPD Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites. Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671). [UniProt]
Specifications
| BEND3 | |
| Polyclonal | |
| Unconjugated | |
| BEND3 | |
| BEN domain containing 3; BEN domain-containing protein 3; Bend3; KIAA1553; mKIAA1553 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 57673 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry | |
| 0.5 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q5T5X7 | |
| BEND3 | |
| Recombinant protein corresponding to Human BEND3 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only