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beta-3 Tubulin Monoclonal Antibody (2G10), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA1118
This item is not returnable.
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Description
MA1-118 was successfully used to detect E18 Sparague Dawley primary cortical neurons. MA1-118 can be used for immunofluorescence analysis of beta III tubulin in the ectoderm derived from human embryonic stem cells. Western blot analysis of MA1-118 detects an ∽50 kDa protein in neuronal-type cells. In bovine, a unknown band at ∽32 kDa is also detected. MA1-118 shows specificity to beta-3 Tubulin and is non-reactive to lysates from non-neuronal cell types (e.g. HeLa cell lysate).
The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
Specifications
| beta-3 Tubulin | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide | |
| Q13509, Q2T9S0, Q4QRB4, Q9ERD7 | |
| LOC100341581, TUBB3 | |
| A synthetic peptide corresponding to amino acids 436-450 from rat neuronal specific beta-3 tubulin. | |
| 100 μg | |
| Primary | |
| Bovine, Guinea Pig, Hamster, Human, Mouse, Porcine, Rabbit, Rat | |
| Antibody | |
| IgG2a |
| Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 2G10 | |
| Unconjugated | |
| TUBB3 | |
| 3200002H15Rik; beta 3 tubulin; beta tubulin 3; beta-4; betaIII-tubulin; CDCBM; CDCBM1; CFEOM3; CFEOM3A; class III beta-tubulin; FEOM3; I79_000194; LOC100341581; M(beta)3; M(beta)6; mc1R; melanocortin receptor 1; Neuron specific beta III Tubulin; neuron-specific class III beta-tubulin; TUBB; Tubb3; TUBB4; tubulin beta; tubulin beta 3 class III; Tubulin beta-3; tubulin beta-3 chain; Tubulin beta-4; Tubulin beta-4 chain; tubulin beta-III; tubulin, beta 3 class III; tubulin, beta, 3; tubulin, beta, 4; Unknown (protein for MGC:134115) | |
| Mouse | |
| Protein A | |
| RUO | |
| 100341581, 100732882, 100760055, 10381, 106509340, 22152, 246118, 768070 | |
| -20°C | |
| Liquid |