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Brepocitinib P-Tosylate, MedChemExpress

MedChemExpress Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.

Brand:  Medchem Express HY-112708A

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Product Code. 16420977

  • 8210.31 SEK / 50mg

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Description

Description

Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.
Specifications

Specifications

Brepocitinib P-Tosylate
White
C25H29F2N7O4S
PF-06700841 P-Tosylate
O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.O=S(C6=CC=C(C)C=C6)(O)=O
561.6
Research
COVID-19-immunoregulation
2140301-96-6
Research
50 mg
DMSO : 62.5 mg/mL (111.29 mM; Need ultrasonic)
561.6
99.69%
Solid
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