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Caspase 6 Monoclonal Antibody (MCH2 14 1-190), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA112558
This item is not returnable.
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Description
A suggested positive control for this product is MCF-7 cell lysate.
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Specifications
| Caspase 6 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.08% sodium azide | |
| P55212 | |
| Casp6 | |
| Recombinant human capase-6 protein. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| MCH2 14 1-190 | |
| Unconjugated | |
| Casp6 | |
| apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 839 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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Product Title
Caspase 6 Monoclonal Antibody (MCH2 14 1-190), Invitrogen™ > 100 μg; Unconjugated
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