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Thermo Scientific™ CellSensor™ ISRE-bla RA-1 Cell Line
The CellSensor™ ISRE-bla RA-1 Cell Line contains the beta-lactamase (bla) gene under the control of the interferon-stimulated response element (ISRE).
Brand: Thermo Scientific™ K1674
This item is not returnable.
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Description
The CellSensor™ ISRE-bla RA-1 Cell Line contains the beta-lactamase (bla) gene under the control of the interferon-stimulated response element (ISRE). This cell line was engineered by lentiviral transduction of an ISRE-bla construct into RA-1 cells. Flow cytometry was then used to isolate a pool of cells responsive to polyinosinic-polycytidylic acid (poly I:C) stimulation. ISRE-bla RA-1 cells have been tested for assay performance using variable assay conditions, including DMSO concentration, cell number, stimulation time, substrate loading time, as well as validated for Z'-factor and EC50 concentrations of poly I:C. Additional testing data using alternate stimuli are also available. Academic and non-profit customers, please inquire for special pricing.
Specifications
| Cell-based beta lactamase reporter gene | |
| CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use. | |
| Fluorescent | |
| beta-lactamase gene under the control of the interferon stimulated response element (ISRE) | |
| 1 Vial | |
| TLR3/TBK1/IRF3 pathway, TBK1, IRF3, TLR3 | |
| CellSensor™ |
| Dividing Cells | |
| CellSensor™ ISRE-bla RA-1 Cell Line, 1Vial, ∽ 5,000,000 cells/vial at 5,000,000 cells/mL Quantity of Cells, ISRE-bla RA-1 Cell Line, Fluorescent Detection Method, CellSensor™ Druggable Target, Suspension Growth Properties, Liquid Nitrogen Storage | |
| Pharma and biopharma, drug discovery and development, target and lead identification and validation, pathway biology, cellular pathway analysis assays, cellsensor™ cellular pathway assays | |
| CellSensor™ | |
| ISRE-bla RA-1 | |
| Cell Line | |
| Signaling Pathway |
For Research Use Only. Not for use in diagnostic procedures.