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  6. Gibco™ CHO CD EfficientFeed™ A AGT™ Nutrient Supplement
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Gibco™ CHO CD EfficientFeed™ A AGT™ Nutrient Supplement

CHO CD EfficientFeed™ A AGT™ Nutrient Supplement

Brand:  Gibco™ A1442002

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Product Code. 15369726

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Description

Description

Gibco™ CHO CD EfficientFeed™ A nutrient supplement is an animal origin-free, chemically defined complete feed formulation that provides up to 2-5 fold improvement in titers used in fed batch versus batch culture. It contains no proteins, hydrolysates, or components of incompletely defined composition. CHO CD EfficientFeed™ A AGT™ (Advanced Granulation Technology™) Kit Nutrient Supplement provides all the benefits of CHO CD EfficientFeed™ A liquid supplement in a simpler to scale up and reconstitute 2-part kit that is primarily AGT™ dry format material.

The AGT™ format is designed for large scale manufacturing and ease of use. This product is also available in liquid form for small scale use and experimentation.
  • Expect up to 2- to 5-fold increases in productivity
  • Avoid issues associated with the use of hydrolysates and other alternatives while gaining superior performance
  • Simplify scale-up by leveraging the value of AGT™ simple reconstitution
  • Achieve performance comparable to original liquid supplement
  • Ready for larger scale use with convenient packaging options (10 L and 100 L)

    Which EfficientFeed™ Nutrient Supplement to Choose?
    Consider the CHO CD Efficient Feed™ Kit when:
  • You are using a base medium with less than 6 g/L glucose and no hydrolysate at day 0

    Consider CHO CD EfficientFeed™ A supplement when:
  • You are currently using CD OptiCHO™ as your base cell growth medium

    Consider CHO CD EfficientFeed™ B supplement when:
  • You are currently using CD CHO as your base cell growth medium

    Consider CD EfficientFeed™ C AGT™ supplement when:
  • You want higher productivity in GS CHO and other selected cell lines
  • You are currently using CD FortiCHO™ as your base cell growth medium
  • You are using a base medium with greater than 6 g/L glucose or a hydrolysate at day 0

    Increased Titers
    CHO CD EfficientFeed™ supplements have been shown to increase titers 2-5 fold versus batch culture, and are an excellent starting point for process development (Figures 1a & 1b). Furthermore, they outperform competitive alternatives, including less consistent hydrolysates (Figures 2, 3a, & 3b).

    Simple Scale-Up and Cost Savings
    The ability to scale up in a dry format provides ease of handling and storage in manufacturing and other bioprocess settings. With AGT™ (Advanced Granulation Technology™) dry format, it is possible to store and use the product even more easily and safely than traditional dry format products. CHO CD EfficientFeed™ A AGT™ supplement is offered in 10 L and 100 L packaging that allows scale-up from the 1 L liquid supplement as a seamless process, as well as allow for cost savings when purchasing production level volumes.

    Comparable Performance to Liquid Supplement
    Equally important as the convenience and simplicity of AGT™ (Advanced Granulation Technology™) dry format is the comparable performance to the liquid CHO CD EfficientFeed™ A version (Figure 4). Both forms have performed similarly in our testing, and the AGT™ version has been used successfully as a prototype in many processes by multiple companies.

    AGT™ Format Ease of Use
    CHO CD EfficientFeed™ A AGT™ Kit Nutrient Supplement delivers dry format scale-up convenience as well as simple reconstitution with approximately 1% concentrated solution add back. For more details, consult the supporting documents provided below.

    For research or further manufacturing use. Not for use in diagnostic procedures.
    TRUSTED_SUSTAINABILITY
    • Specifications

    Specifications

    Store at 2 to 8°C
    Animal Origin-free, Chemically-defined, Protein-free, Serum-free
    AGT
    Serum-Free
    Sodium Pyruvate, Sodium Bicarbonate
    Low
    AGT™, EfficientFeed™
    100 L
    Chemically Defined Nutrient Feeding Supplement
    Solubility
    CHO
    Suspension Cell Culture
    Nutrient Supplement
    Non-sterile
    No Glutamine, No Phenol Red, No Insulin, No Sodium Pyruvate
    Ropak Bucket
    Cell Culture Grade, Qualified for Further Manufacturing, Research Grade
    100 L
    Wet Ice
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    For Research Use or Further Manufacturing. Not for use in diagnostic procedures.