missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ CLP 257
Selective KCC2 activator
2810.00 SEK - 10755.00 SEK
Specifications
| Chemical Name or Material | (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone |
|---|---|
| CAS | 1181081-71-9 |
| Target | KCC2 Activators |
| Molecular Formula | C14H14FN3O2S |
| Formula Weight | 307.34 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18700468
|
Tocris Bioscience™
5242/10 |
10 mg |
2810.00 SEK
10mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
18797199
|
Tocris Bioscience™
5242/50 |
50 mg |
10755.00 SEK
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Selective KCC2 K+-Cl- cotransporter activator (EC50 = 616 nM). Exhibits selectivity for KCC2 over other KCC family members, NKCC1 and GABAA receptors, as well as 55 other receptors. Enhances Cl- transport and increases KCC2 plasma membrane expression in spinal slices with reduced KCC2 function. Alleviates hypersensitivity in rats with peripheral nerve injury.Specifications
| (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone | |
| KCC2 Activators | |
| 307.34 |
| 1181081-71-9 | |
| C14H14FN3O2S | |
| >98% |
Safety and Handling
Recommended Storage : Store at 4°C