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Tango™ CNR2-bla U2OS DA Assay Kit
Tango™ CNR2-bla U2OS DA Assay Kit contains the human Cannabinoid Receptor 2 (CNR2) linked to a TEV protease site.
Brand: Tango™ K1567
Additional Details : Weight : 0.05000kg
Description
- Gene Symbol: CNR2
- Accession Number: NM_001841
- Cytoplasmic Tail: Tail from AVPR2 GPCR
- Population Status: Single Cell Clone Origin
- Includes: Tango™ CNR2-bla U2OS DA cells, LiveBLAzer™-FRET B/G Loading Kit, 70 μg, Solution D, Tango™ CNR2-bla U2OS Assay Protocol, LiveBLAzer™-FRET B/G Loading Protocol, Certificate of Analysis
- The Tango™ CNR2-bla U2OS DA (Division Arrested) cells and Tango™ CNR2-bla U2OS cells contain the human Cannabinoid Receptor 2 (CNR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
- The Tango™ CNR2-bla U2OS cells and the Tango™ CNR2-bla U2OS DA cells have been functionally validated for Z' factor and EC50 concentrations of CP-55940. In addition, Tango™ CNR2-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section. DA cells are irreversibly division arrested using a low-dose treatment of Mitomycin C, and have no apparent toxicity or change in cellular signal transduction.
Specifications
| Liquid Nitrogen | |
| GPCRs | |
| Division-Arrested Cells Assay Kit |
| Fluorescent | |
| 1 Plate |