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Cytokeratin 8 Monoclonal Antibody (8A5D12), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA515460
This item is not returnable.
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Description
MA5-15460 targets Cytokeratin 8 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15460 immunogen is purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli. MA5-15460 detects Cytokeratin 8 which has a predicted molecular weight of approximately 54kDa.
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Specifications
| Cytokeratin 8 | |
| Monoclonal | |
| Conc. Not Determined | |
| ascites with 0.03% sodium azide | |
| P05787 | |
| KRT8 | |
| Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli. | |
| RUO | |
| 3856 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot | |
| 8A5D12 | |
| Unconjugated | |
| KRT8 | |
| AA960620; AL022697; AU019895; CARD2; cb186; CK8; CK-8; CYK8; CYKER; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin-8; cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; K2C8; K8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-8; KO; Krt-2.8; Krt2-8; krt8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; type II cytokeratin A (no.8); type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8 | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |