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Decitabine, Tocris Bioscience™

Product Code. 18752484
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

DNA methyltransferase inhibitor

Cytosine analog that once incorporated into DNA acts as a suicide substrate for DNA methyltransferase. Inhibits DNA methyltransferase and results in DNA hypomethylation and activation of silent genes. Chemotherapeutic agent; suppresses growth of human tumor cell lines. Demethylates differentiation-related genes; reverses embryonic stem cell differentiation.

Chemical Identifiers

CAS 2353-33-5
Molecular Formula C9H13N3O4
Molecular Weight (g/mol) 227.22
MDL Number MFCD00006547
InChI Key CKTSBUTUHBMZGZ-SHYZEUOFSA-N
Synonym decitabine, 5-aza-2'-deoxycytidine, dacogen, 5-azadeoxycytidine, 2'-deoxy-5-azacytidine, azadc, dezocitidine, 5-aza-cdr, 5-aza-dc, dacogen tn
PubChem CID 451668
ChEBI CHEBI:50131
IUPAC Name 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
SMILES NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1

Specifications

Quantity 10 mg
Formula Weight 228.21
Percent Purity >99%
Chemical Name or Material Decitabine
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