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Tocris Bioscience™ des-His1-[Glu9)-Glucagon (1-29) amide
Glucagon receptor antagonist
Brand: Tocris Bioscience™ 2216/1
3536.02 SEK valid until 2024-12-16
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This item is not returnable.
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Description
des-His1-[Glu9]-Glucagon (1-29) amide is a glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitro. Blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats.Specifications
| 95% | |
| des-His1-[Glu9)-Glucagon (1-29) amide | |
| des-His1-[Glu9]-Glucagon (1-29) amide | |
| Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2 |
| Store at -20°C | |
| 3358.68 | |
| 1 mg |
For Research Use Only