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Desmocollin 2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13876-1-AP-20UL
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Description
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.Specifications
| Desmocollin 2 | |
| Polyclonal | |
| Unconjugated | |
| DSC2 | |
| ARVD11, Cadherin family member 2, CDHF2, desmocollin 2, Desmocollin 3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, DG2, DGII/III, DSC2, DSC3 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 13506, 1824 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P55292, Q02487 | |
| DSC2 | |
| Desmocollin 2 Fusion Protein Ag4956 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |