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Thermo Scientific Chemicals DL-1,4-Dithiothreitol, 99%, for biochemistry
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Quantity:
1 g
5 g
25 g
100 g
500 g
Beschreibung
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
- 1,4-Dithiothreitol (DTT or Cleland's reagent) reduces disulfide bonds in proteins, leading to loss of native conformation
- DTT is not stable in solution and should be prepared in small aliquots prior to use; the use of EDTA in the solution can increase the half-life of DTT
- Typically used at a final concentration of 0.1M for protein stabilization; recommended to create a 1M stock
Applications
- Protects thiol groups from oxidation and acts as a chemical chelator in solution; maintains proteins in the denatured state
- Common applications include SDS-page electrophoresis and protein isolation
Spezifikation
Spezifikation
| Absorbance | (1 M soln. in water), (1 M soln. in water) at 0nm, 0.035 max. at 500nm |
| Melting Point | 39°C to 44°C |
| Color | White |
| Infrared Spectrum | Authentic |
| Assay Percent Range | 0.99 |
| Molecular Formula | C4H10O2S2 |
| Linear Formula | HSCH2CH(OH)CH(OH)CH2SH |
| Quantity | 1 g |
| Beilstein | 01, III, 2360 |
| Merck Index | 15, 3419 |
| Mehr anzeigen |
Sicherheit und Handhabung
Produktidentifikator
- DL-1,4-Dithiothreitol
- Warning
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- H302-Harmful if swallowed.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
- P302+P352-IF ON SKIN: Wash with plenty of water/.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
RUO – Research Use Only
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