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Tocris Bioscience™ DMH2
Type I BMP receptor inhibitor
Brand: Tocris Bioscience™ 5580/50
9095.22 SEK valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
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Description
DMH2 is a type I BMP receptor inhibitor (Ki values are <1, 5.4 and 43 nM for ALK6, ALK3 and ALK2, respectively). Exhibits >30-fold selectivity over ALK4, ALK5, BMPR2, AMPK and VEGFR2. Also binds to TGFBR2 (Ki = 85 nM). Decreases growth and induces cell death of H1299 non-small cell lung carcinoma cells in vitro. Enhances liver regeneration in vivo.Specifications
| 4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | |
| 50 mg | |
| C27H25N5O2 | |
| >98% |
| 1206711-14-9 | |
| BMP and Other Activin Receptor Inhibitors | |
| 451.52 |