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Eurofins DiscoverX DYRK1A Protein, Active
Active, N-terminal GST-tagged, recombinant, human DYRK1A, full length, for use in Kinase Assays
Brand: Eurofins DiscoverX 14-951
Additional Details : Weight : 4.70710kg
Description
Protein serine-threonine kinase Dyrk1a (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, PSK47), predominately expressed in the central nervous system, is a dual-specificity kinase and emerge roles in cell growth and development. Human clone has been isolated from the Downs' syndrome critical region. Dyrk1a inhibition may provide a therapeutic approach for the neurological defects of Down syndrome.
GenBank NM_130436.2
Specifications
| mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. | |
| 10 μg | |
| Recombinant | |
| Recombinant enzyme expressed in Sf21 insect cells | |
| ≥65% |
| 112 kDa | |
| Human | |
| N-terminal GST | |
| Full-length | |
| DYRK1A, active |