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EB1 Monoclonal Antibody (1A11/4), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen 412100

Product Code. 10282323

  • 4550.00 SEK / Each

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For Research Use Only. All usage must comply with product instructions.

This item is not returnable. View return policy

Description

Description

EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes and regulate the dynamics and organization of microtubules. The MAPRE genes encode the EB1 family proteins. The human MAPRE genes MAPRE1, MAPRE2, and MAPRE3 code for EB1, RP1, and EBF3 proteins, respectively. EB1 family members appear to be expressed ubiquitously. The EB1 (MAPRE1) gene, at 20q11. 2, is fused to MLL in an adult patient with pro-B acute lymphoblastic leukemia. EB1 is a microtubule-associated protein that interacts with the colorectal adenomatous polyposis coli tumor-suppressor protein and plays important roles in regulating microtubule dynamics, cell polarity, and chromosome stability.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

EB1
Monoclonal
0.5 mg/mL
PBS with 0.1% sodium azide; pH 7.4
Q15691, Q61166, Q66HR2
Mapre1
Recombinant protein encompassing the N-terminal domain of the human EB1 protein
100 μg
Primary
Canine, Human, Mouse, Rat
Antibody
IgG2b κ
ELISA, Immunocytochemistry, Western Blot
1A11/4
Unconjugated
Mapre1
5530600P05Rik; adenomatosis polyposis coli binding protein Eb1; adenomatous polyposis coli-binding protein EB1; AI462499; AI504412; APC-binding protein EB1; AW260097; BIM1p; D2Ertd459e; Eb1; end-binding protein 1; Mapre1; MGC117374; MGC129946; microtubule associated protein RP/EB family member 1; Microtubule-associated protein RP/EB family member 1; microtubule-associated protein RP/EB family member 1-like protein; microtubule-associated protein, RP/EB family, member 1
Mouse
Protein A
RUO
100685707, 114764, 13589, 22919
-20°C
Liquid
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