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GeneBLAzer™ ENDRB-NFAT-bla HEK 293T Cells
GeneBLAzer™ ENDRB-NFAT-bla HEK 293T Cells contain the human Endothelin Type B Recpetor (EDNRB).
Brand: GeneBLAzer™ K1727
Additional Details : Weight : 0.01000kg
Description
- Gene Symbol: EDNRB
- Accession Number: NM_000115.1
- Population Status: Single Cell Clone Origin
- GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells contain the human Endothelin Type B Recpetor (EDNRB) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line. CellSensor™ NFAT-bla HEK293T cells (Cat. no. K1538) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
- The GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells are functionally validated for Z' and EC50concentrations of ET-1. In addition, GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
- The ENDRB receptor mediates signaling of endothelin proteins that regulate several critical biological processes, including the development and function of blood vessels, the production of certain hormones, and the stimulation of cell growth and division. Defects in EDNRB mediated signaling have been implicated in a wide range of diseases, including cancer, hypertension and cardiovascular disorders.
Specifications
| Liquid Nitrogen | |
| GPCRs | |
| 2 x 106 Cells |
| Fluorescent | |
| EDNRB-NFAT-bla HEK293T cells, EDNRB-NFAT-bla HEK293T Assay Protocol, Certificate of Analysis | |
| Dividing Cells |