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Epstein Barr Virus Antibody Cocktail, Invitrogen™
Antibody Cocktail
Brand: Invitrogen MA512172
This item is not returnable.
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Description
MA5-12172 targets Epstein-Barr Virus in IHC (P) applications and shows reactivity with Bacteria samples. The MA5-12172 immunogen is eBV-encoded recombinant latent membrane protein.
Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
Specifications
| Epstein Barr Virus | |
| Cocktail | |
| Conc. Not Determined | |
| tissue culture supernatant with 0.09% sodium azide | |
| Mouse | |
| 500 μL | |
| Primary | |
| 4° C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| CS1, CS2, CS3, CS4, CS2, CS3, CS4 | |
| Unconjugated | |
| EBV | |
| EBV-encoded recombinant latent membrane protein | |
| RUO | |
| Virus | |
| Antibody | |
| IgG1 κ |
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