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β-Estradiol, MP Biomedicals™

Product Code. 11404942
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Quantity:
250 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

β-Estradiol is a potent mammalian estrogenic hormone produced by the ovary. Triggers the production of gonadotropins, leading to ovulation.

Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation.

  • The major estrogen secreted by the premenopausal ovary.
  • Exposure to estradiol increases breast cancer incidence and proliferation.
TRUSTED_SUSTAINABILITY

Specifications

CAS 50-28-2
Melting Point 173°C to 179°C
Molecular Formula C18H24O2
Quantity 250 mg
Synonym estradiol, beta-estradiol, 17beta-estradiol, oestradiol, dihydrofolliculin, estrace, ovocyclin, progynon, dihydrotheelin, dihydroxyestrin
Solubility Information Almost insoluble in water (50mg/mL; clear, colorless solution). Freely soluble in alcohol; soluble in acetone, dioxane, other organic solvents; solutions of fixed alkali hydroxides; sparingly soluble in vegetable oils; soluble in methanol:CHCl3 (1:1).
InChI Key VOXZDWNPVJITMN-ZBRFXRBCSA-N
Optical Rotation +76.8 (Concentration = 1, Solvent = Dioxane) (Lit.)
SMILES CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
IUPAC Name (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Molecular Weight (g/mol) 272.388
PubChem CID 5757
ChEBI CHEBI:16469
Formula Weight 272.39g/mol
Grade Cell Culture Reagent
Physical Form Powder
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