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Fulvestrant, MedChemExpress
MedChemExpress Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.
Brand: Medchem Express HY-13636
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Description
Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.Specifications
| Fulvestrant | |
| White | |
| C32H47F5O3S | |
| ICI 182780 ZD 9238 ZM 182780 | |
| C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2 | |
| 606.77 | |
| Research | |
| Cancer-programmed cell death |
| 129453-61-8 | |
| Research | |
| 100 mg | |
| DMSO : 250 mg/mL (412.02 mM; Need ultrasonic) | |
| 606.77 | |
| 95.0% | |
| Solid |
Research purposes only