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STEMCELL Technologies G418

Antibiotic for selecting transfected mammalian cells

Brand:  STEMCELL Technologies 03812

Encompass_Preferred

Product Code. 17120002

  • 2636.55 SEK / 250mg

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Description

Description

  • Antibiotic G418 is an aminoglycoside related to gentamicin and is toxic to bacteria, yeast, higher plants, mammalian cells, protozoans, and helminths
  • G418 binds to 80S ribosomes in prokaryotic and eukaryotic cells and inhibits protein synthesis, resulting in cell death
  • Resistance to the antibiotic is conferred by aminoglycoside-3-phosphotransferase
  • Vectors containing the G418 resistance gene (neo) are commonly used for transfecting eukaryotic cells, with selection of transfected cells achieved by culturing them in the presence of G418
  • Cells may exhibit variable resistance to the antibiotic and can take up to a week to die
  • The G418 antibiotic is suitable for use in cell culture for the selection and maintenance of G418-resistant clones when using ClonaCell™-TCS Medium (Catalog #03814), ClonaCell™-CHO CD Medium (Catalog #03815), ClonaCell™-CHO ACF Medium (Catalog #03816), ClonaCell™­CHO CD Liquid Medium (Catalog #03817), or other cell culture media
Specifications

Specifications

108321-42-2
250 mg
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