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GAB2 Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 29272-1-AP-150UL

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Product Code. 17221446

  • 4721.67 SEK / 150µL

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Description

Description

Growth factor receptor-bound protein 2 (GAB2), an adaptor protein, belongs to the Gab family and is involved in various biologic processes. Gab2 mainly mediates phosphatidylinositol 3-kinase (PI3K) and extracellular signal-regulated kinase (ERK) signaling pathways. Furthermore, Gab2 governs tumorigenic signaling and is a novel potential therapeutic target in leukemia, breast cancer, ovarian cancer, and melanoma. Gab2 is the major 98-kDa phosphoprotein associated with SHP-2, PI 3-kinase, and Grb2 in normal human lymphocytes. (PMID: 32269703, PMID: 28842424, PMID: 28420432, PMID: 10849428)

Specifications

Specifications

GAB2
Polyclonal
Unconjugated
150 μL
9846
Liquid
Western Blot, Immunohistochemistry, ELISA
400 μg/mL
Rabbit
Primary
Human
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