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Galectin 3 Monoclonal Antibody (A3A12), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA1940
This item is not returnable.
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Description
MA1-940 detects galectin-3 from human, mouse and rat tissues. MA1-940 has been successfully used in Western blot, immunohistochemistry, immunofluorescence, immunocytochemistry and ELISA procedures. By Western blot, this antibody detects an ∽30 kDa protein representing galectin-3 from Jurkat cells transfected with human galectin-3. Immunohistochemical staining of galectin-3 in rat olfactory bulb with MA1-940 yields a pattern consistent with nuclear and plasma membrane staining. This antibody is not suitable for mouse NIH-3T3 in Western blot analysis. This antibody also detects a non-specific band in Hela cell lysates at ∽21 kDa. MA1-940 antigen is full length recombinant human galectin-3. The epitope for this antibody has been mapped to the first 58 amino acids of galectin-3.
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Specifications
| Galectin 3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| P08699, P16110, P17931 | |
| LGALS3 | |
| Full length recombinant human galectin-3. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot | |
| A3A12 | |
| Unconjugated | |
| LGALS3 | |
| 35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen | |
| Mouse | |
| purified | |
| RUO | |
| 16854, 3958, 83781 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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