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Thermo Scientific™ GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 Cells
GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells contain the human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Brand: Thermo Scientific™ K1847
Description
GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells contain the human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), (Accession No. NM_000867) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells contain a beta-lactamase reporter gene under control of the NFAT Response Element. The GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells are functionally validated for Z'-factor and EC50 concentrations of 5-HT (Figure 1). In addition, GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions.
Specifications
NM_000867.2 | |
Dividing Cells | |
GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 Cells, 8 x 106 Cells, CHO-K1 Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage | |
FRET | |
G-Protein Coupled Receptor (GPCR) | |
Single Cell Clone Origin | |
8 x 106 Cells | |
CHO-K1 | |
CHO-K1 Cells | |
GeneBLAzer™ |
Cell-based beta lactamase reporter gene | |
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells • GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 Assay Protocol • Certificate of Analysis The GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
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Fluorescence | |
HTR2B | |
GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).. Includes: GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells, GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 Assay Protocol, Certificate of Analysis | |
GeneBLAzer™ | |
End Point | |
HTR2B | |
CHO-K1 | |
GPCR |
For Research Use Only. Not for use in diagnostic procedures.